Collagen alpha-2(IV) chain Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Collagen alpha-2(IV) chain |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | caprylic acid ammonium sulfate precipitate |
| Size | 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous level of total Collagen alpha-2(IV) chain polyclonal antibody. Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Ref.13 Ref.17 Ref.18 Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity.It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity.Ligand for alphavbeta3 and alphavbeta5 integrins. |
| Immunogen | Immunogen: Recombinant Human Alkaline phosphatase, tissue-nonspecific isozyme |
| Other Names | [COL4A2] |
| Gene, Accession # | Gene ID: 1284, NCBI: NP_001837.2, UniProt: P08572 |
| Catalog # | MBS9416091 |
| Price | $320 |
| Order / More Info | Collagen alpha-2(IV) chain Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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