Edit |   |
---|---|
Antigenic Specificity | IGF1R (Phospho-Tyr1161) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of IGF1R when Phospho occurs at Tyr1161. IGF1R (Insulin Like Growth Factor 1 Receptor) is a Protein Coding gene. Diseases associated with IGF1R include Insulin-Like Growth Factor I and Leprechaunism. Among its related pathways are Transcription Androgen Receptor nuclear signaling and p70S6K Signaling. This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced trans |
Immunogen | Immunogen: Synthesized peptide derived from part region of human IGF1R (Phospho-Tyr1161) Antibody protein |
Other Names | [Rabbit IGF1R (Phospho-Tyr1161); Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221] |
Gene, Accession # | [IGF1R], Gene ID: 3480, NCBI: NP_000866.1, UniProt: P08069 |
Catalog # | MBS9709469 |
Price | $130, $220, $325 |
Order / More Info | IGF1R (Phospho-Tyr1161) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |