Mouse CD54/ICAM-1-APC Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD54/ICAM-1-APC
Clone[YN1/1.7.4]
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2b, kappa
Formatunconjugated
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry, Immunohistochemistry (Frozen sections), Immunoprecipitation, In vitro blocking studies 1, Western Blot
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DescriptionSpecificity: Mouse CD54/ICAM-1, Mr 95 kDa. CD54, a member of the immunoglobulin superfamily of cell surface receptors and also known as Intercellular Adhesion Molecule-1 (ICAM-1), is a type I transmembrane glycoprotein that mediates important cell/cell interactions. CD54 is expressed on endothelial cells, dendritic cells, keratinocytes and lymphocytes. Its expression is upregulated by inflammatory mediators such as IFN-gamma, IL-1, TNF-alpha, lipopolysaccharide and phorbol esters. Endothelial CD54 contributes to the extravasation of leukocytes from blood vessels, particularly in areas of inflammation. CD54 on antigen-presenting cells contributes to antigen-specific T-cell activation, presumably by enhancing interactions between T cell and a
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #MBS670210
Price$240
Order / More InfoMouse CD54/ICAM-1-APC Antibody from MYBIOSOURCE INC.
Product Specific References1. Takei, F. 1985. J. Immunol. 134:1403.2. Horley, K.J., C. Carpenito, B. Baker, F. Takei. 1989. EMBO. J. 8:2889.3. Welder, Clayton A., D.H.S. Lee, F. Takei. 1993. J. Immunol. 150:2203.4. Qin, Lan, et. al. 1996. J. Immunol. 157:5016.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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