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Antigenic Specificity | AAK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: AAK1 Polyclonal Antibody detects endogenous levels of AAK1 protein. Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. AAK1 encodes a member (AP2 associated kinase 1) of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human AAK1 at AA range: 240-320 |
Other Names | [Rabbit AAK1; AAK1; KIAA1048; AP2-associated protein kinase 1; Adaptor-associated kinase 1] |
Gene, Accession # | [AAK1], Gene ID: 22848, NCBI: NP_055726.3, UniProt: Q2M2I8 |
Catalog # | MBS9701296 |
Price | $130, $220, $325 |
Order / More Info | AAK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |