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Antigenic Specificity | ACKR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1, TARC and also for the malaria parasites P.vivax and P.knowlesi. May r |
Immunogen | Immunogen: Recombinant human Atypical chemokine receptor 1 protrin (1-63AA) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-27815 / sc-27813 |
Other Names | [Atypical chemokine receptor 1; Duffy antigen/chemokine receptor; Glycoprotein D; Plasmodium vivax receptor; ACKR1; DARC; FY; GPD], [ACKR1; ACKR1; FY; Dfy; GPD; DARC; GpFy; CCBP1; CD234; WBCQ1; DARC; FY; GPD; GpFy] |
Gene, Accession # | [ACKR1], Gene ID: 2532, NCBI: NP_001116423.1, UniProt: Q16570 |
Catalog # | MBS1492710 |
Price | $160, $235 |
Order / More Info | ACKR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |