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Antigenic Specificity | UTX - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, human, mouse, porcine, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against UTX. It was validated on Western BlotTarget Description: UTX is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. UTX plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitent with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UTX |
Other Names | [lysine-specific demethylase 6A isoform 3; Lysine-specific demethylase 6A; lysine-specific demethylase 6A; lysine demethylase 6A; Histone demethylase UTX; Ubiquitously-transcribed TPR protein on the X chromosome; Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein] |
Gene, Accession # | [KDM6A], Gene ID: 7403, NCBI: NP_066963, UniProt: O15550 |
Catalog # | MBS3204652 |
Price | $335 |
Order / More Info | UTX - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |