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Antigenic Specificity | MGEA5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MGEA5 antibody detects endogenous levels of total MGEA5. Function: Isoform 1: Cleaves GlcNAc but not GalNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:11148210). Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:24088714).Subunit Structure: Monomer (PubMed:11788610). Interacts with CLOCK (By similarity).Post-translational Modifications: Proteolytically cleaved by caspase-3 during apoptosis. The fragments interact with each other; cleavage does not decrease enzyme activity.Similarity: Belongs to the glycosyl hydrolase 84 family. |
Immunogen | Immunogen: A synthesized peptide derived from human MGEA5 Subcellular Location: Cytoplasm and Nucleus. Tissue Specificity: Ubiquitous. Shows highest expression in the brain, placenta and pancreas. |
Other Names | [Beta-hexosaminidase; Beta-N-acetylglucosaminidase; Beta-N-acetylhexosaminidase; Bifunctional protein NCOAT; HEXC; Hyaluronidase in meningioma; KIAA0679; MEA5; Meningioma expressed antigen 5; Meningioma-expressed antigen 5; MGEA 5; Mgea5; N-acetyl-beta-D-glucosaminidase; N-acetyl-beta-glucosaminidase; NCOAT; Nuclear cytoplasmic O GlcNAcase and acetyltransferase; Nuclear cytoplasmic O-GlcNAcase and acetyltransferase; OGA; OGA_HUMAN; Protein O-GlcNAcase] |
Gene, Accession # | [MGEA5], Gene ID: 10724, NCBI: NP_001135906.1, UniProt: O60502 |
Catalog # | MBS9608795 |
Price | $240, $280 |
Order / More Info | MGEA5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |