SamD10 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SamD10 antibody, protein, ELISA kits.
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| Antigenic Specificity | SamD10 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody recognizes the protein SamD10. The antibody can also recognize SamD12. SamD10 and SamD12 are two recently discovered homolog proteins consisting of a SAM domain. These proteins are also known as Hyphen (HYP) or Aveugle (Ave) and they have been demonstrated to interact with the SAM domain of the Connector enhancer of KSR (CNK) downstream of RAS but a a step upstream of RAF. A role for these proteins downstream of EGFR during eye and wing development of Drosophila has also been demonstrated. Heterodimerization of CNK/SAM has been shown to facilitate the recruitment of a KSR/MEK complex to CNK and bridge KSR/MEK to RAF which greatly enhances RAS-mediated RAF activation. |
| Immunogen | n/a |
| Other Names | [Sterile alpha motif (SAM) domain-containing protein 10; Hyphen D10; HYPD10; Aveugle], [SAMD10; SAMD10; dJ591C20; C20orf136; dJ591C20.7; C20orf136; SAM domain-containing protein 10] |
| Gene, Accession # | [SamD10], Gene ID: 140700, NCBI: NP_542188.1, UniProt: Q9BYL1 |
| Catalog # | MBS588216 |
| Price | $330 |
| Order / More Info | SamD10 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Claperon A and Therrien M-KSR and CNK: two scaffolds regulating RAS-mediated RAF activation. 2. Douziech M-A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila. 3. Roignant JY-The novel SAM domain protein Aveugle is required for Raf activation in the Drosophila EGF receptor signaling pathway. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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