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Antigenic Specificity | Human BIM (C-TERMINAL) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item specifically recognises an epitope within the C-terminal (CT) region of the AD, ACD and ABCD isoforms of human BIM, otherwise known as Bcl-2 interacting mediator of cell death.. . BIM is an apoptotic activator protein and member of the Bcl-2 family, which forms heterodimers with several anti-apoptotic proteins including BCL2, BHRF1, and MCL1, but not with the pro-apoptotic proteins BAD, BAX or BAK. BIM can be induced by nerve growth factor (NGF) and also by forkhead transcription factor FKHR-L1, implicating BIM in both neuronal and lymphocyte apoptosis. MBS224109 specifically recognises an epitope within the C-terminal (CT) region of the AD, ACD and ABCD isoforms of human BIM, otherwise known as Bcl-2 interacting mediator of cel |
Immunogen | Immunogen: Synthetic peptide sequence C-FNAYYARRLEK from the C-Terminal region of BIM (NP 619528; NP 996886; NP 619529). Buffer Solution: TRIS buffered saline Antiserum Preparation: Antiserum to human BIM (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human |
Other Names | [bcl-2-like protein 11 isoform 11; Bcl-2-like protein 11; bcl-2-like protein 11; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; bcl-2-related ovarian death agonist; BCL2-like 11 (apoptosis facilitator); Bcl2-interacting mediator of cell death], [BCL2L11; BCL2L11; BAM; BIM; BOD; BIM; Bcl2-L-11] |
Gene, Accession # | [BIM], Gene ID: 10018, NCBI: NP_001191035.1, UniProt: O43521 |
Catalog # | MBS224109 |
Price | $550 |
Order / More Info | Human BIM (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |