APP Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | APP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Amyloid beta (Abeta) precursor protein (APP) is a 100-140 kDa transmembrane glycoprotein that exists as several isoforms (1). The amino acid sequence of APP contains the amyloid domain (Abeta), which can be released by a two-step proteolytic cleavage (1). The extracellular deposition and accumulation of the released Abeta fragments form the main components of amyloid plaques in Alzheimer's disease (1). APP can be phosphorylated at several sites, which may affect the proteolytic processing and secretion of this protein (2-5). Phosphorylation at Thr668 (at a position corresponding to the APP695 isoform) by cyclin-dependent kinase is cell cycle-dependent and peaks during G2/M-phase (4). APP phosphorylated at Thr668 exists in adult rat brain an |
| Immunogen | Immunogen: N term -peptide of human APP Calculated Molecular Weight: 87kDa |
| Other Names | [APP; beta-Amyloid: APP/b-Amyloid; APP; AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN2; amyloidP; Amyloid beta A4 protein; A4; Beta Amyloid], [APP; APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)] |
| Gene, Accession # | [APP], Gene ID: 351, NCBI: P05067.3, UniProt: P05067 |
| Catalog # | MBS125346 |
| Price | $200, $275, $430 |
| Order / More Info | APP Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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