Edit |   |
---|---|
Antigenic Specificity | MLLT11 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MLLT11 antibody detects endogenous levels of total MLLT11. Function: Cofactor for the transcription factor TCF7 (PubMed:26079538). Involved in regulation of lymphoid development by driving multipotent hematopoietic progenitor cells towards a T cell fate (PubMed:21715312).Subunit Structure: Interacts with HSPA8 and LAMP2 isoform A; the interaction may target MLLT11 for degradation via chaperone-mediated autophagy (PubMed:24880125). Interacts with TCF7 (PubMed:26079538).Post-translational Modifications: Ubiquitinated, leading to degradation.Similarity: Belongs to the MLLT11 family. |
Immunogen | Immunogen: A synthesized peptide derived from human MLLT11 Subcellular Location: Nucleus; Cytoskeleton Tissue Specificity: Expressed in myoepithelial cells of normal breast tissue (at protein level) (PubMed:26079538). Highly expressed in thymus (PubMed:7833468). Expressed in colon, small intestine, prostate and ovary. Not detected in peripheral blood lymphocytes and spleen (PubMed:7833468). Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Zebr |
Other Names | [AF1Q; AF1Q_HUMAN; ALL1 fused gene from chromosome 1q; MLLT 11; MLLT11; Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila) translocated to 11; Protein AF1q; RP11 316M1.10] |
Gene, Accession # | [MLLT11], Gene ID: 10962, NCBI: NP_006809.1, UniProt: Q13015 |
Catalog # | MBS9608629 |
Price | $240, $280 |
Order / More Info | MLLT11 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |