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Antigenic Specificity | FIGNL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FIGNL1 antibody detects endogenous levels of total FIGNL1. Function: Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner. May regulate osteoblast proliferation and differentiation (PubMed:23754376). May play a role in the control of male meiosis dynamic (By similarity).Subunit Structure: Hexamer (By similarity). Interacts (via N-terminal one-half region) with RAD51; the interaction is direct. Interacts (via N-terminal one-half region) with SPIDR (via the C-terminal region); the interaction is direct.Similarity: The N-terminus is necessary for its recruitment to DNA damage sites. Belongs to t |
Immunogen | Immunogen: A synthesized peptide derived from human FIGNL1 Subcellular Location: Nucleus |
Other Names | [Fidgetin like protein 1] |
Gene, Accession # | [FIGNL1], Gene ID: 63979, NCBI: NP_001036227.1, UniProt: Q6PIW4 |
Catalog # | MBS9609834 |
Price | $240, $280 |
Order / More Info | FIGNL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |