FIGNL1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFIGNL1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: FIGNL1 antibody detects endogenous levels of total FIGNL1. Function: Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner. May regulate osteoblast proliferation and differentiation (PubMed:23754376). May play a role in the control of male meiosis dynamic (By similarity).Subunit Structure: Hexamer (By similarity). Interacts (via N-terminal one-half region) with RAD51; the interaction is direct. Interacts (via N-terminal one-half region) with SPIDR (via the C-terminal region); the interaction is direct.Similarity: The N-terminus is necessary for its recruitment to DNA damage sites. Belongs to t
ImmunogenImmunogen: A synthesized peptide derived from human FIGNL1 Subcellular Location: Nucleus
Other Names[Fidgetin like protein 1]
Gene, Accession #[FIGNL1], Gene ID: 63979, NCBI: NP_001036227.1, UniProt: Q6PIW4
Catalog #MBS9609834
Price$240, $280
Order / More InfoFIGNL1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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