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Antigenic Specificity | SP1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter Plays an essential role in the regulation of FE65 gene expression (By si |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse SP1 |
Other Names | [transcription factor Sp1; Transcription factor Sp1; transcription factor Sp1; trans-acting transcription factor 1] |
Gene, Accession # | [SP1], Gene ID: 20683, NCBI: NP_038700.2, UniProt: O89090 |
Catalog # | MBS3223534 |
Price | $335 |
Order / More Info | SP1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |