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Antigenic Specificity | Human GRM8 / MGLUR8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Bat, chimpanzee, horse, human, monkey, rabbit. predicted reactivity: mouse, rat, dog, hamster, chicken (at least 90% immunogen sequence identity) |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human GRM8 / MGLUR8. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except GRM4 (61%). Metabotropic Glutamate Receptor GRM8 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. |
Immunogen | Immunogen Description: Synthetic 18 amino acid peptide from N-terminal extracellular domain of human GRM8 / MGLUR8. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Baboon, Monkey, Galago, Marmoset, Shrew, Bat, Rabbit, Horse, Armadillo (100%). |
Other Names | [GRM8 / MGLUR8 (N-Terminus) IHC-plus; GRM8; GLUR8; GPRC1H; MGlu8; MGLUR8; Human GRM8; MGLUR8], [MGLUR8] |
Gene, Accession # | [GRM8], Gene ID: 2918, NCBI: NP_000836.2, UniProt: O00222 |
Catalog # | MBS247022 |
Price | $530 |
Order / More Info | Human GRM8 / MGLUR8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |