CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of 140kDa, which is identified as the complement receptor 2(CR2)/CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro.CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha.CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. |
| Immunogen | Immunogen: Recombinant fragment (around aa 44-196) of human CR2 (CD21) protein (exact sequence is proprietary) |
| Other Names | [CD21; Complement C3d receptor (C3DR); Complement Receptor type 2 (CR2); CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; SLEB9] |
| Gene, Accession # | [CD21], Gene ID: 1380, NCBI: P20023.2, UniProt: P20023 |
| Catalog # | MBS4380812 |
| Price | $190, $340, $340 |
| Order / More Info | CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Otsuka, M., et al. 2004. Role of CD21 antigen in diffuse large B-cell lymphoma and its clinical significance. Br. J. Haematol. 127: 416 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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