HIPK3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | HIPK3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.1 mg |
| Concentration | 0.5-1.5 ug/ul in antibody stabilization buffer |
| Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Overview: Serine/threonine-protein kinase involved in transcription regulation, apoptosis and steroidogenic gene expression. Phosphorylates JUN and RUNX2. Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. The phosphorylation of NR5A1 activates SF1 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. In osteoblasts, supports transcription activation: phosphorylates RUNX2 that synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).Structure: Belongs to the protein kinase superfamily. |
| Immunogen | Immunogen: Synthetic peptide taken within amino aci region 860-910 on human Homeodomain-interacting protein kinase 3 protein. Conjugation: Unconjugated |
| Other Names | [Affinity Purified Homeodomain-interacting protein kinase 3; Androgen receptor interacting nuclear protein kinase; ANPK; DYRK6; Fas-interacting serine/threonine-protein kinase; FIST; FIST3; Hipk3; homeodomain interacting protein kinase 3; Homolog of protein kinase YAK1; PKY; RP24 297H17.5; YAK1] |
| Gene, Accession # | [HIPK3], Gene ID: 10114, NCBI: NP_001041665.1, UniProt: Q9H422 |
| Catalog # | MBS5400422 |
| Price | $390 |
| Order / More Info | HIPK3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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