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Antigenic Specificity | TRPV6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 0.67 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Affinity Purified Transient receptor potential cation channel, subfamily V, member 6 Antibody. Calcium selective cation channel probably involved in Ca2+ uptake in various tissues, including Ca2+ reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca2+-dependent and a slower Ca2+-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg2+ in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating. |
Immunogen | Immunogen: Synthetic peptide taken from the region within amino acids 700-732 of TRPV6 protein. The peptide was covalently modified to acheive desired antigenicity. Modified peptide was covalently coupled to a carrier protein by heterobifunctional cross linker for immunogen preparation. Expression: Abundantly expressed in pancreas and placenta, and to a much lesser extend in stomach and kidney. Not detected in intestine. |
Other Names | [ABPZF; Alu binding protein with zinc finger domain; Calcium channel CaT1; Calcium transport protein 1; CaT L; CaT1; ecac; ECaC2; Epithelial apical membrane calcium transporter/channel CaT1; Epithelial calcium channel 2; HSA277909; LP6728; NUDC; Transient receptor potential cation channel subfamily V member 6; TrpV6; ZFAB], [TRPV6; TRPV6; CAT1; CATL; ZFAB; ECAC2; ABP/ZF; LP6728; HSA277909; ECAC2; TrpV6; CaT-L; CaT1; ECaC2] |
Gene, Accession # | [TRPV6], Gene ID: 55503, NCBI: EAW51899.1 |
Catalog # | MBS540489 |
Price | $390 |
Order / More Info | TRPV6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |