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Antigenic Specificity | Guinea Pig MBP (68-86) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | 1ug/ul |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antiserum recognizes MBP in demyelinated nerve tissues. Immunohistochemical analysis of lesioned rat spinal cord indictaes a high level of specificity for this antiserum. Myelin is a membrane characteristic of the nervous tissue and functions as an insulator to increase the velocity of the stimuli being transmitted between a nerve cell body and its target. Myelin isolated from human and bovine nervous tissue is composed of approximately 80% lipid and 20% protein, and 30% of the protein fraction constitutes myelin basic protein (MBP). MBP is an 'intrinsically unstructured' protein with a high proportion (approximately 75%) of random coil, but postulated to have core elements of beta-sheet and alpha-helix. MBP is a major protein in CNS m |
Immunogen | Immunogen: A synthetic peptide (YG SLPQKSQRSQ DENPVV, aa: 68-86) as part of guinea pig MBP protein conjugated to KLH Storage Buffer: PBS, pH 7.4 with 0.02% sodium azide. |
Other Names | [MBP, partial; Myelin basic protein; myelin basic protein; Golli-MBP; proline-rich proteoglycan 2; myelin basic protein; Myelin A1 protein; Myelin membrane encephalitogenic protein] |
Gene, Accession # | [MBP], Gene ID: 4155, NCBI: CAG46717.1, UniProt: P02686 |
Catalog # | MBS4152704 |
Price | $515 |
Order / More Info | Guinea Pig MBP (68-86) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |