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Antigenic Specificity | CD83, Human |
Clone | ELBE-1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immuno Assay (IA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Monoclonal antibody ELBE-1 recognizes human CD83. CD83 is a cell surface marker predominantly expressed on mature DCs. Expression has been found on circulating and tissue DCs. Additionally CD83 is found on activated B and T lymphocytes. Human CD83 is composed of 205 amino acids but has, due to extensive glycosylation, a molecular weight of ca 45 kDa. CD83 is expressed as a conserved a noncovalently associated single chain molecule membrane protein. CD83 is considered a marker for fully matured dendritic cells in the peripheral circulation. An essential role has not been found. However, its function primarily lies in the regulation of T- and B-cell maturation and the regulation of their peripheral responses. CD83 is supposed to function as a |
Immunogen | Immunogen: huCD83Ig fusion protein |
Other Names | [B-cell activation protein; Cell surface protein HB15], [CD83; CD83; BL11; HB15; hCD83] |
Gene, Accession # | [CD83], Gene ID: 9308, NCBI: NP_004224.1, UniProt: Q01151 |
Catalog # | MBS584768 |
Price | $520 |
Order / More Info | CD83, Human Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Papp, S et al. A New Monoclonal Anti-human CD83 Antibody for Flow Cytometry, Western Blot Analysis, and ELISA. Monoclon Antib Immunodiagn Immunother 2013, 32: 98. |