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Antigenic Specificity | Phospho-Keratin 17 (Tyr98) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: zebrafish, bovine, horse, sheep, rabbit, dog, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Keratin 17 (Tyr98) Antibody detects endogenous levels of Keratin 17 only when phosphorylated at Tyr98. Description: Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia |
Immunogen | Immunogen: A synthesized peptide derived from human Keratin 17 around the phosphorylation site of Tyr98. Tissue Specificity: Expressed in the outer root sheath and medulla region of hair follicle specifically from eyebrow and beard, digital pulp, nail matrix and nail bed epithelium, mucosal stratified squamous epithelia and in basal cells of oral epithelium, palmoplantar epidermis and sweat and mammary glands. Also expressed in myoepithelium of prostate, basal layer of urinary bladder, cambial c |
Other Names | [39.1; CK 17; CK-17; Cytokeratin-17; K1C17_HUMAN; Keratin 17; keratin 17 epitope S1; keratin 17 epitope S2; keratin 17 epitope S4; Keratin 17, type I; Keratin; Keratin type I cytoskeletal 17; keratin, type i cytoskeletal 17 [version 1]; Keratin-17; KRT17; PC; PC2; PCHC1; type I cytoskeletal 17] |
Gene, Accession # | [K17], Gene ID: 3872, NCBI: NP_000413.1, UniProt: Q04695 |
Catalog # | MBS9610713 |
Price | $225, $280, $340 |
Order / More Info | Phospho-Keratin 17 (Tyr98) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |