CRTC2 (C-term), 664-693 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CRTC2 (C-term), 664-693 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CRTC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 664-693 amino acids from the C-terminal region of human CRTC2. Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cel |
| Immunogen | n/a |
| Other Names | [CREB-regulated transcription coactivator 2; Transducer of regulated cAMP response element-binding protein 2; TORC-2; Transducer of CREB protein 2; CRTC2; TORC2] |
| Gene, Accession # | [CRTC2], Gene ID: 200186, NCBI: NP_859066.1, UniProt: Q53ET0 |
| Catalog # | MBS9209679 |
| Price | $165, $370 |
| Order / More Info | CRTC2 (C-term), 664-693 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Nakatsu, Y., et al. J. Biol. Chem. 285(43):33018-33027(2010) Kaizuka, T., et al. J. Biol. Chem. 285(26):20109-20116(2010) Lyo, D., et al. Biochem. Biophys. Res. Commun. 396(2):562-565(2010) Lu, M., et al. J. Am. Soc. Nephrol. 21(5):811-818(2010) Roulin, D., et al. Mol. Cancer 9, 57 (2010) : |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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