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Antigenic Specificity | Mouse CD103 |
Clone | [2E7] |
Host Species | Hamster |
Reactive Species | n/a |
Isotype | IgG |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Hamster anti Mouse CD103 antibody, clone 2E7 recognizes mouse CD103, otherwise known as Integrin alpha-E. CD103 binds Integrin beta 7 to form the heterodimeric integrin molecule aEbeta7. This complex is sometimes referred to as CD103, though strictly speaking CD103 only refers to the alpha chain. The beta 7 subunit can also interact with other integrin alpha chains. The aEbeta7 complex is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. CD103 is expressed on intestinal intraepithelial lymphocytes and is highly expressed on regulatory T cells.Hamster anti Mouse CD103 antibody, clone 2E7 has been reported to also recognize the aEbeta7 complex. |
Immunogen | Immunogen: Mouse intestinal intraepithelial lymphocytes Buffer Solution: Phosphate buffered saline Target Species: Mouse |
Other Names | [integrin alpha-E isoform 1; Integrin alpha-E; integrin alpha-E; integrin alpha M290; integrin alpha E, epithelial-associated; Integrin alpha M290; CD_antigen: CD103Cleaved into the following 2 chains:Integrin alpha-E light chain; Integrin alpha-E heavy chain], [Itgae; Itgae; CD103; aM290; alpha-E1; A530055J10; alpha-M290] |
Gene, Accession # | [CD103], Gene ID: 16407, NCBI: NP_032425.2, UniProt: Q60677 |
Catalog # | MBS219538 |
Price | $300 |
Order / More Info | Mouse CD103 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |