LAMP1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | LAMP1 |
| Clone | [Ly1C6] |
| Host Species | Mouse |
| Reactive Species | rat, hamster |
| Isotype | IgG1 |
| Format | streptavidin conjugate |
| Size | 0.1 mg |
| Concentration | 1mg/mL |
| Applications | Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background Info: Detects an ~120kDa protein corresponding to the molecular mass of LAMP1 on SDS PAGE immunoblots. Scientific Background: Lysosme associated membrane proteins, or LAMP1 and LAMP2, are major constituents of the lysosomal membrane. The two have closely related structures, with 37% sequence homology (2). They are both transmembrane glycoproteins that are localized primarily in lysosomes and late endosomes. Newly synthesized molecules are mostly transported from the trans-Golgi network directly to endosomes and then to lysosomes. A second pathway involves the lamps being delivered from the Golgi to the cell surface, and then along the endocytic pathway to the lysosomes. A minor pathway involves transport via the plasma membrane ( |
| Immunogen | n/a |
| Other Names | [CD107; CD107a; LAMPA; LGP120; IgpA; Lysosome-associated membrane glycoprotein 1; CD107 antigen-like family member A; 120 kDa lysosomal membrane glycoprotein; Lamp-1], [Lamp1; Lamp1; LGP120; Lamp-1; LAMP-1; Lysosome-associated membrane protein 1; LGP-120] |
| Gene, Accession # | Gene ID: 25328, NCBI: NP_036989.1, UniProt: P14562 |
| Catalog # | MBS800014 |
| Price | $425 |
| Order / More Info | LAMP1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Grutzkau, A. et al (2004) Cytometry A. 61(10): 62-68. 2. Furuta, K. et al. (1999) EMBO J. 17(5):1304-14. 3. Rohrer, J. et al. (1996) J Cell Biol. 132(4): 565-76. 4. Kannan, K., et al. (1996) Cell Immunol. 171: 10-19. 5. Lewis, V., et al. (1985) J. Cell Biol. 100: 1839-1847. 6. Jones, K.A., et al. (2004) Exp Cell Res 295(2): 512-524. 1. Hiasa, M. et al. (2014). Essential role of vesicular nucleotide transporter in vesicular storage and release of nucleotides in platelets. Physiol Rep. 2(6). pii: e12034. doi: 10.14814/phy2.12034 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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