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Antigenic Specificity | TLR2 |
Clone | [1070CT4.2.3.2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1,kappa |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TLR2 Antibody is generated from a mouse immunized with a recombinant protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed:21078852, PubMed:17889651). Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also activate immune cells and promote apoptosis in response to the lipid moiety of lipoproteins (PubMed:10426995, PubMed:10426996). Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdor |
Immunogen | n/a |
Other Names | [Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; CD282; TLR2; TIL4] |
Gene, Accession # | [TLR2], Gene ID: 7097, NCBI: NP_001305716.1, UniProt: O60603 |
Catalog # | MBS9230994 |
Price | $165, $370 |
Order / More Info | TLR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | Chaudhary P.M.,et al.Blood 91:4020-4027 (1998). Rock F.L.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:588-593 (1998). Yang R.-B.,et al.Nature 395:284-288 (1998). Nakajima T.,et al.Immunogenetics 60:727-735 (2008). Georgel P.,et al.PLoS ONE 4:E7803-E7803 (2009). |