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Antigenic Specificity | ATXN7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ATXN7 antibody detects endogenous levels of total ATXN7. Function: Acts as component of the STAGA transcription coactivator-HAT complex. Mediates the interaction of STAGA complex with the CRX and is involved in CRX-dependent gene activation. Necessary for microtubule cytoskeleton stabilization.Subunit Structure: Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP, TAF9 and ATXN7. The STAGA core complex is associated with a subcomplex required for histone deubiquitination composed of ATXN7L3, ENY2 and USP22. Interacts with SORBS1, PSMC1 and CRX. Interacts with TRRAP, GCN5L2 and TAF10. Interacts with alpha tubulin.Post- |
Immunogen | Immunogen: A synthesized peptide derived from human ATXN7 Subcellular Location: Cytoplasmic (isoform b) and Nuclear (isoform a) Tissue Specificity: Isoform a and isoform b are expressed in CNS, but isoform a is expressed predominantly in the peripherical tissues. Isoform b is also highly expressed in the frontal lobe, skeletal muscle and spinal cord and is expressed at a lower level in the lung, lymphoblast and intestine. Predicted Cross Reactivity: Pig, Horse, Rabbit, Dog, Chicken Similarity: P |
Other Names | [ADCAII; ATXN 7; OPCA III; OPCA3; SCA 7; SCA7; Spinocerebellar Ataxia 7; Spinocerebellar ataxia type 7 protein] |
Gene, Accession # | [ATXN7], Gene ID: 6314, NCBI: NP_000324.1, UniProt: O15265 |
Catalog # | MBS9609550 |
Price | $240, $280 |
Order / More Info | ATXN7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |