E-Cadherin (CDH1)/CD324 (Intercellular Junction Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityE-Cadherin (CDH1)/CD324 (Intercellular Junction Marker)
Clone[CDH1/3256]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunohistochemistry (IHC) Paraffin
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DescriptionRecognizes a protein of 120-80kDa, identified as E-cadherin. Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as -catenin, to regulate cadherin function. E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combin
ImmunogenImmunogen: Recombinant fragment of human CDH1 protein (around aa 567-691) (exact sequence is proprietary)
Other Names[Arc 1; cadherin 1 type 1 E-cadherin; Cadherin1; CAM 120/80; CDHE; E-Cad/CTF3; E-cadherin; ECAD; Epithelial cadherin; epithelial calcium dependent adhesion protein; Liver cell adhesion molecule (LCAM); Uvomorulin (UVO)]
Gene, Accession #[CDH1], Gene ID: 999, NCBI: NP_004351.1, UniProt: P12830
Catalog #MBS4381452
Price$190, $340, $340
Order / More InfoE-Cadherin (CDH1)/CD324 (Intercellular Junction Marker) Antibody from MYBIOSOURCE INC.
Product Specific References1. Jaggi M. et al. Cancer Res. 2005, 65: 483-492. 2. Rios-Doria, J et al. J. Biol. Chem 2003; 278: 372-1379.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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