JIP-2/IB-2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-JIP-2/IB-2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | JIP-2/IB-2 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoblot, Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes human, mouse, and rat JIP-2/IB-2. It does not cross-react with JIP-1/IB-1. The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells and may function as a regulator of vesicle transport through interactions with the JNK-signaling components and motor proteins. It is expressed mainly in the cerebellum, pituitary gland, occipital lobe, and the amygdala of the brain, but also in the pancreas, including in insulin-secreting cells. |
| Immunogen | Immunogen: Fusion protein corresponding to aa 226-421of mouse JIP-2/IB-2. This sequence is 94% identical to rat, 86% identical to human, and >50% identical to JIP-1. |
| Other Names | [C-Jun-amino-terminal kinase-interacting protein 2; C-Jun-amino-terminal kinase-interacting protein 2; C-Jun-amino-terminal kinase-interacting protein 2; mitogen-activated protein kinase 8 interacting protein 2; Islet-brain-2; IB-2; JNK MAP kinase scaffold protein 2; Mitogen-activated protein kinase 8-interacting protein 2], [Mapk8ip2; Mapk8ip2; IB2; Jip2; R75148; AI847694; AW049958; 3230402N03Rik; Ib2; Jip2; JIP-2; JNK-interacting protein 2; IB-2] |
| Gene, Accession # | [JIP-2/IB-2], Gene ID: 60597, NCBI: NP_068740.3, UniProt: Q9ERE9 |
| Catalog # | MBS191340 |
| Price | $410 |
| Order / More Info | JIP-2/IB-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies