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Antigenic Specificity | HTR2C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illne |
Immunogen | Immunogen: A synthetic peptide of human HTR2C |
Other Names | [5-HT1C; 5-HT2C; 5-HTR2C; 5HTR2C; HTR1C] |
Gene, Accession # | [HTR2C], Gene ID: 3358, NCBI: P28335.1, UniProt: P28335 |
Catalog # | MBS9131806 |
Price | $275, $430 |
Order / More Info | HTR2C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |