FBLN5 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityFBLN5
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman, mouse
IsotypeIgG1
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: FBLN5 antibody detects endogenous levels of total FBLN5. Description: FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.Function: Essential for elastic fiber formation, is involved in the assembl
ImmunogenImmunogen: Purified recombinant fragment of human FBLN5 expressed in E. Coli Subcellular Location: Secreted. Tissue Specificity: Expressed in skin fibroblasts (at protein level)(PubMed:17035250). Expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes (PubMed:10428823).
Other Names[ADCL2; ARCL1A; ARMD3; Dance; Developmental arteries and neural crest EGF like protein; Developmental arteries and neural crest EGF-like protein; EVEC; Fbln5; FBLN5_HUMAN; FIBL 5; FIBL-5; Fibulin-5; FLJ90059; UP50; Urine p50 protein]
Gene, Accession #[FBLN5], Gene ID: 10516, NCBI: NP_006320.2, UniProt: Q9UBX5
Catalog #MBS9602653
Price$235, $295, $370
Order / More InfoFBLN5 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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