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Antigenic Specificity | MNK2 (MKNK2) (N-term), 70-100 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MNK2 (MKNK2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-100 amino acids from the N-terminal region of human MNK2 (MKNK2). MAP kinase-interacting kinase 1 (Mnk1) and Mnk2, members of the Ser/Thr protein kinase family, bind tightly to the growth factor-regulated MAP kinases, Erk1 and Erk2. Erk and p38 phosphorylate MNK1 and Mnk2, which stimulates their in vitro kinase activity toward a substrate, eukaryotic initiation factor-4E (eIF-4E). Overexpression of Mnk2 results in increased phosphorylation of endogenous eIF-4E, showing that it can act as an eIF-4E kinase in vivo. Mnk2 may play a role in the response to environmental stress and cytokines. This ubiquitiously expressed protein appe |
Immunogen | n/a |
Other Names | [MAP kinase-interacting serine/threonine-protein kinase 2; MAP kinase signal-integrating kinase 2; MAPK signal-integrating kinase 2; Mnk2; MKNK2; GPRK7; MNK2] |
Gene, Accession # | [MKNK2], Gene ID: 2872, NCBI: NP_060042.2, UniProt: Q9HBH9 |
Catalog # | MBS9201079 |
Price | $165, $370 |
Order / More Info | MNK2 (MKNK2) (N-term), 70-100 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |