ICAD Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ICAD |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ICAD Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A human DNA fragmentation factor (DFF) was identified recently which was cleaved by caspase-3 during apoptosis. Mouse homologue of human DFF was identified as a DNase inhibitor designated ICAD, for inhibitor of caspase-activated DNase. Upon cleavage of DFF/ICAD, a caspase activated deoxyribonuclease (CAD) is released and activated and eventually causes the degradation of DNA in the nuclei. Therefore, the cleava |
| Immunogen | Immunogen: ICAD antibody was raised against a 20 amino acid peptide near the carboxy terminus of mouse ICAD. Buffer: ICAD Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [ICAD; ICAD; DFF35; Dff45; ICAD-L; ICAD-S; A330085O09Rik; Icad; DNA fragmentation factor subunit alpha; DNA fragmentation factor 45 kDa subunit; DFF-45; DNA fragmentation factor, alpha subunit], [Dffa; Dffa; ICAD; DFF35; Dff45; ICAD-L; ICAD-S; A330085O09Rik; Icad; DFF-45; ICAD] |
| Gene, Accession # | [Dffa], Gene ID: 13347, NCBI: O54786.1, UniProt: O54786 |
| Catalog # | MBS150237 |
| Price | $375 |
| Order / More Info | ICAD Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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