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Antigenic Specificity | Menin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Menin Antibody detects endogenous levels of total Menin. Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL)-containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes. |
Immunogen | Immunogen: A synthesized peptide derived from human Menin |
Other Names | [MEA1; Men1; Menin; Multiple Endocrine Adenomatosis 1; Multiple Endocrine Neoplasia 1; SCG2; Suppressor Candidate Gene 2; Wermer syndrome; ZES] |
Gene, Accession # | Gene ID: 4221, NCBI: NP_000235.2, UniProt: O00255 |
Catalog # | MBS4750955 |
Price | $335 |
Order / More Info | Menin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |