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Antigenic Specificity | Human VEGF-D |
Clone | [5D31] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) - Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects human VEGF-D in western blots. No cross-reactivity is shown with VEGF and VEGF-B. VEGF-D, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymphangiogesis, and can also affect vascular permeability. VEGF-D is highly expressed in the lung, heart, small intestine and fetal lung, and at lower levels in the skeletal muscle, colon, and pancreas. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-D may play a role in the formation of the venous and lymphatic vascular systems. It also participates in the |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with recombinant human VEGF-D recombinant protein. The IgG2 fraction of culture supernatant was purified by Protein G affinity chromatography. |
Other Names | [human VEGF-D (#7E79)], [FIGF; FIGF; VEGFD; VEGF-D; VEGFD; VEGF-D; FIGF] |
Gene, Accession # | [VEGF-D], Gene ID: 2277, NCBI: NP_004460.1, UniProt: O43915 |
Catalog # | MBS690962 |
Price | $490 |
Order / More Info | Human VEGF-D Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |