Mouse Dnmt3L, 389-421 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Dnmt3L, 389-421 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse (predicted reactivity: rat) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Dnmt3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-421 amino acids from mouse Dnmt3L. mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger. |
| Immunogen | n/a |
| Other Names | [DNA (cytosine-5)-methyltransferase 3-like; Dnmt3l] |
| Gene, Accession # | [Dnmt3l], Gene ID: 54427, NCBI: NP_001075164.1, UniProt: Q9CWR8 |
| Catalog # | MBS9207537 |
| Price | $165, $370 |
| Order / More Info | Mouse Dnmt3L, 389-421 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Okazaki, Y., et al., Nature 420(6915):563-573 (2002). Bourc'his, D., et al., Science 294(5551):2536-2539 (2001). Aapola, U., et al., Cytogenet. Cell Genet. 92 (1-2), 122-126 (2001). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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