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Antigenic Specificity | C1QBP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total C1QBP protein. Is believed to be a multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome biogenesis, regulation of apoptosis, transcriptional regulation and pre-mRNA splicing. At the cell surface is thought to act as an endothelial receptor for plasma proteins of the complement and kallikrein-kinin cascades. Putative receptor for C1q; specifically binds to the globular heads of C1q thus inhibiting C1; may perform the receptor function through a complex with C1qR/CD93. In complex with cytokeratin-1/KRT1 is a high affinity receptor for kininogen-1/HMWK. Can also bind other plasma proteins, such as coagulation factor XII leading to its autoact |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human C1QBP. |
Other Names | [C1q globular domain-binding protein; complement component 1; q subcomponent binding protein; Complement component 1; Q subcomponent binding protein] |
Gene, Accession # | [C1QBP], Gene ID: 708, NCBI: NP_001203.1, UniProt: Q07021 |
Catalog # | MBS9404333 |
Price | $200, $255 |
Order / More Info | C1QBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |