Dnmt1 - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDnmt1 - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against Dnmt1. It was validated on Western BlotTarget Description: Dnmt1 methylates CpG residues.Dnmt1 preferentially methylates hemimethylated DNA. Dnmt1 associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance.Dnmt1 associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones.Dnmt1 mediates transcriptional repression by direct binding to HDAC2. In association with DNMT3B and via the recruitment of CTCFL/B
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse Dnmt1
Other Names[DNA (cytosine-5)-methyltransferase 1 isoform 2; DNA (cytosine-5)-methyltransferase 1; DNA (cytosine-5)-methyltransferase 1; DNA methyltransferase (cytosine-5) 1; DNA methyltransferase MmuI; DNA MTase MmuI; M.MmuI; MCMT]
Gene, Accession #[DNMT1], Gene ID: 13433, NCBI: NP_034196, UniProt: P13864
Catalog #MBS3203426
Price$335
Order / More InfoDnmt1 - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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