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Antigenic Specificity | TP53INP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TP53INP1 protein. Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response. Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function. Positively regulates p53/TP53 and p73/TP73 |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human TP53INP1. |
Other Names | [Tumor protein p53-inducible nuclear protein 1; p53-dependent damage-inducible nuclear protein 1; p53DINP1; Stress-induced protein; TP53INP1] |
Gene, Accession # | [TP53INP1], Gene ID: 94241, NCBI: NP_001129205.1, UniProt: Q96A56 |
Catalog # | MBS9404619 |
Price | $200, $255 |
Order / More Info | TP53INP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |