CD59, Human Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-CD59, Human antibody, protein, ELISA kits.
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| Antigenic Specificity | CD59, Human |
| Clone | MEM-43 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The antibody is the prototypic antibody for the CD59 determinant, a PI-linked glycoprotein of 18-25 kDa, which is broadly expressed on most types of cells. The antigen is the major complement-protecting molecule of human cells. It is expressed on all leukocytes, erythrocytes and most other cell types. Binding of this antibody inhibits the complement-protecting activity of CD59. CD59 is one of the complement regulatory membrane proteins that is missing in Paroxysmal Nocturnal Haemoglobinuria (PNH). Anti CD59 reagents may be useful in the differential diagnosis of PNH type II and PNH type I. Recently a role for CD59 in LPS signal transduction has been reported in keratinocytes. The antibody reacts with well defined epitop |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [CD59] |
| Catalog # | MBS584198 |
| Price | $610 |
| Order / More Info | CD59, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Yakamoto, T et al; Lipopolysaccharide signal transduction in oral keratinocytes - involvement of CD59 but not CD14. Cellular Signalling 2003, 15: 861 2. Horesji, V et al; Folia Biol 1986, 34: 12 3. Knapp, W et al; Leucocyte Typing IV, Oxford University Press 1989 4. Schlossman, S et al; Leucocyte Typing IV, Oxford University Press 1995 5. Cebecauer, M et al; Incorporation of leucocyte GPI-anchored proteins and protein tyrosine kinases into lipid-rich membrane domains of COS-7 cells. Biochem Biophys Res Commun 1998, 234: 1998 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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