SUFU Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-SUFU antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | SUFU |
| Clone | [1783CT536.263.29] |
| Host Species | Mouse |
| Reactive Species | human, African Green monkey |
| Isotype | IgG1,k |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SUFU antibody is generated from a mouse immunized with a recombinant protein of human SUFU. Negative regulator in the hedgehog signaling pathway. Down-regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full length form of GLI3 (GLI3FL). GLI3FL is complexed with SUFU in the cytoplasm and is maintained in a neutra |
| Immunogen | n/a |
| Other Names | [Suppressor of fused homolog; SUFUH; SUFU] |
| Gene, Accession # | [SUFU], Gene ID: 51684, NCBI: NP_001171604.1, UniProt: Q9UMX1 |
| Catalog # | MBS9230955 |
| Price | $165, $370 |
| Order / More Info | SUFU Antibody from MYBIOSOURCE INC. |
| Product Specific References | Stone D.M.,et al.J. Cell Sci. 112:4437-4448 (1999). Kogerman P.,et al.Nat. Cell Biol. 1:312-319 (1999). Taylor M.D.,et al.Nat. Genet. 31:306-310 (2002). Clark H.F.,et al.Genome Res. 13:2265-2270 (2003). Deloukas P.,et al.Nature 429:375-381 (2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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