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Antigenic Specificity | MEK Kinase-1 (Phospho Thr1402) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-MEK Kinase-1 (T1402) Polyclonal Antibody detects endogenous levels of MEK Kinase-1 protein only when phosphorylated at T1402. The protein encoded by MAP3K1 is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. |
Immunogen | Immunogen: Synthesized peptide derived from human MEK Kinase-1 around the phosphorylation site of T1402 |
Other Names | [Rabbit MEK Kinase-1 (phospho Thr1402); MAP3K1; MAPKKK1; MEKK; Mitogen-activated protein kinase kinase kinase 1; MAPK/ERK kinase kinase 1; MEK kinase 1; MEKK 1] |
Gene, Accession # | [MEKK1], Gene ID: 4214, NCBI: NP_005912.1, UniProt: Q13233 |
Catalog # | MBS9705863 |
Price | $130, $220, $325 |
Order / More Info | MEK Kinase-1 (Phospho Thr1402) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |