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Antigenic Specificity | UBE2D2 (N-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This UBE2D2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 44-76 amino acids from the N-terminal region of human UBE2D2. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP- induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria b |
Immunogen | n/a |
Other Names | [Ubiquitin-conjugating enzyme E2 D2; Ubiquitin carrier protein D2; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; Ubiquitin-protein ligase D2; p53-regulated ubiquitin-conjugating enzyme 1; UBE2D2; PUBC1; UBC4; UBC5B; UBCH4; UBCH5B] |
Gene, Accession # | [UBE2D2], Gene ID: 7322, NCBI: NP_003330.1, UniProt: P62837 |
Catalog # | MBS9213327 |
Price | $165, $370 |
Order / More Info | UBE2D2 (N-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Jensen J.P.,et al.J. Biol. Chem. 270:30408-30414(1995). Rolfe M.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:3264-3268(1995). Guinn B.-A.,et al.Biochem. Biophys. Res. Commun. 335:1293-1304(2005). Yin Y.,et al.Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). |