Phospho-MAPK8/MAPK9/MAPK10 (T183/T183/T221) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Phospho-MAPK8/MAPK9/MAPK10 (T183/T183/T221) antibody, protein, ELISA kits.
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| Antigenic Specificity | Phospho-MAPK8/MAPK9/MAPK10 (T183/T183/T221) |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | IgG |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. Phosphorylates the replication licensing factor CDT1, inhibiting the interaction between CDT1 and the histone H4 acetylase HBO1 |
| Immunogen | Immunogen: A synthesized peptide derived from human Phospho-MAPK8/MAPK9/MAPK10 (T183/T183/T221) |
| Other Names | [Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK8; JNK1; PRKM8; SAPK1; SAPK1C] |
| Gene, Accession # | [MAPK8/MAPK9/MAPK10], Gene ID: 5599, NCBI: NP_001265476.1, UniProt: P45983 |
| Catalog # | MBS7114862 |
| Price | $185, $265 |
| Order / More Info | Phospho-MAPK8/MAPK9/MAPK10 (T183/T183/T221) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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