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Antigenic Specificity | BRMS1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes endogenous levels of BRMS1 protein. BRMS1 is a transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. |
Immunogen | Immunogen: BRMS1 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BRMS1 as the immunogen |
Other Names | [Purified BRMS1; BRMS1; BRMS1; Breast cancer metastasis-suppressor 1] |
Gene, Accession # | [BRMS1], Gene ID: 25855 |
Catalog # | MBS5315538 |
Price | $270 |
Order / More Info | BRMS1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |