Hrk BH3 Domain, 15-50 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHrk BH3 Domain, 15-50
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis Hrk BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-50 amino acids from human Hrk BH3 Domain. Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL.
Immunogenn/a
Other Names[Activator of apoptosis harakiri; BH3-interacting domain-containing protein 3; Neuronal death protein DP5; HRK; BID3]
Gene, Accession #[HRK], Gene ID: 8739, NCBI: NP_003797.1, UniProt: O00198
Catalog #MBS9212528
Price$165, $370
Order / More InfoHrk BH3 Domain, 15-50 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesWakabayashi, T., et al., Neurosci. Lett. 318(2):77-80 (2002). Inohara, N., et al., EMBO J. 16(7):1686-1694 (1997).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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