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Antigenic Specificity | JMJD1C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody will not cross-react with JMJD1A or JMJD1B. The jumonji domain containing 1C protein (JMJD1C) was initially discovered in silico, and later suggested to be a candidate gene for autism. Like the related proteins JMJD1A and JMJD1B, JMJD1C is a histone H3K9 demethylase implicated in the nuclear hormone receptor-based transcriptional regulation. JMJD1C mRNA is highly expressed in undifferentiated embryonic stem (ES) cells as well as pancreatic islet, diffuse-type gastric cancer, and other tissues and tumors. The JMJD1C gene promoter contain bHLH-, AP-1-, and POU5F1-binding sites, and as preferential expression of POU5F1 has been reported in ES cells, pancreatic islet, and diffuse-type gastric cancer, it has been suggested that POU |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 20 amino acid peptide from near the amino terminus of human JMJD1C. |
Other Names | [Jumonji domain containing 1C protein, TRIP8] |
Gene, Accession # | [JMJD1C], Gene ID: 221037, NCBI: NP_116165 |
Catalog # | MBS9403021 |
Price | $320 |
Order / More Info | JMJD1C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |