Edit |   |
---|---|
Antigenic Specificity | Human Protein Phosphatase 1G |
Clone | [Pk1G6AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: PPM1G is part of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways. PPM1G is accountable for the dephosphorylation of Pre-mRNA splicing factors, an important factor for the formation of functional spliceosome. PPM1G regulates cell cycle progression. PPM1G mediates histone dephosphorylation/exchange in response to DNA damage or checkpoint recovery in higher eukaryotes. The degradation of p21/WAF1 induced by PPM1G is mediated in a proteasome-dependent manner. Protein phosphatase 1G regulates assembly and function of the beta-catenin degradation complex. |
Immunogen | Immunogen: Anti-human PPM1G mAb is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PPM1G amino acids 317-546 purified from E Coli. |
Other Names | [PPM1G; Protein Phosphatase 1G, Mouse Human; Protein Phosphatase 1G; PP2CG; PPP2CG; MGC1675; MGC2870; PP2C GAMMA; EC 3.1.3.16; Protein phosphatase 2C isoform gamma; PP2C-gamma; Protein phosphatase magnesium-dependent 1 gamma; Protein phosphatase 1C; PPM1G; PPM1C], [PPM1G; PPM1G; PP2CG; PPP2CG; PP2CGAMMA; PPM1C; PP2C-gamma] |
Gene, Accession # | [PPM1G], Gene ID: 5496, NCBI: NP_817092.1 |
Catalog # | MBS140304 |
Price | $140, $205, $505 |
Order / More Info | Human Protein Phosphatase 1G Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |