Edit |   |
---|---|
Antigenic Specificity | Human G protein-coupled receptor kinase 6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro). |
Immunogen | Immunogen: Recombinant human G protein-coupled receptor kinase 6 protein (1-170aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-566 / sc-13080 |
Other Names | [GRK6; G protein-coupled receptor kinase GRK6; GPRK6], [GRK6; GRK6; GPRK6; GPRK6] |
Gene, Accession # | [GRK6], Gene ID: 2870, NCBI: NP_001004105.1, UniProt: P43250 |
Catalog # | MBS1493672 |
Price | $120, $160 |
Order / More Info | Human G protein-coupled receptor kinase 6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |