Human G protein-coupled receptor kinase 6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman G protein-coupled receptor kinase 6
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionSpecifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
ImmunogenImmunogen: Recombinant human G protein-coupled receptor kinase 6 protein (1-170aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-566 / sc-13080
Other Names[GRK6; G protein-coupled receptor kinase GRK6; GPRK6], [GRK6; GRK6; GPRK6; GPRK6]
Gene, Accession #[GRK6], Gene ID: 2870, NCBI: NP_001004105.1, UniProt: P43250
Catalog #MBS1493672
Price$120, $160
Order / More InfoHuman G protein-coupled receptor kinase 6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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