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Antigenic Specificity | Zyxin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | Peptide ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alterna |
Immunogen | Immunogen: Synthetic peptide conjugated to KLH |
Other Names | [zyxin; Zyxin; zyxin; zyxin-2; zyxin; Zyxin-2], [ZYX; ZYX; ESP-2; HED-2] |
Gene, Accession # | [Zyxin], Gene ID: 7791, NCBI: NP_001010972.1 |
Catalog # | MBS415590 |
Price | $230 |
Order / More Info | Zyxin Antibody from MYBIOSOURCE INC. |
Product Specific References | Reinhard M, Jouvenal K, Tripier D Identification,purification,andcharacterization of a zyxin-related protein that binds the focal adhesion and microfilament protein VASP(vasodilator-stimulated phosphoprotein) Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7956-60 |