Zyxin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityZyxin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein A purified
Size0.1 mL
Concentration100ug/100ul
ApplicationsPeptide ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
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DescriptionFocal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alterna
ImmunogenImmunogen: Synthetic peptide conjugated to KLH
Other Names[zyxin; Zyxin; zyxin; zyxin-2; zyxin; Zyxin-2], [ZYX; ZYX; ESP-2; HED-2]
Gene, Accession #[Zyxin], Gene ID: 7791, NCBI: NP_001010972.1
Catalog #MBS415590
Price$230
Order / More InfoZyxin Antibody from MYBIOSOURCE INC.
Product Specific ReferencesReinhard M, Jouvenal K, Tripier D Identification,purification,andcharacterization of a zyxin-related protein that binds the focal adhesion and microfilament protein VASP(vasodilator-stimulated phosphoprotein) Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7956-60
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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