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Antigenic Specificity | IGFBP-3 (Phospho-Ser183) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of IGFBP-3 only when phosphorylated at serine 183. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.Zhang Q, Steinle JJ (2013)Invest Ophthalmol Vis Sci 54, 3052-7. Cobb LJ, Liu B, Lee KW, Cohen P (2006) Cancer Res 66, 10878-84. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of serine 183(K-D-S(p)-Q-R) derived from Human IGFBP-3. |
Other Names | [IBP-3; IBP3; IGF-binding protein 3; IGFBP3; Insulin-like growth factor binding protein 3 precursor] |
Gene, Accession # | [IGFBP-3], Gene ID: 3486, NCBI: NP_000589.2, UniProt: P17936 |
Catalog # | MBS9414357 |
Price | $200, $255 |
Order / More Info | IGFBP-3 (Phospho-Ser183) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |