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Antigenic Specificity | Mouse Rad50 (C-term), 911-938 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Rad50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 911-938 amino acids from the C-terminal region of mouse Rad50. Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity |
Immunogen | n/a |
Other Names | [DNA repair protein RAD50; mRad50; 36--; Rad50] |
Gene, Accession # | [Rad50], NCBI: P70388.1, UniProt: P70388 |
Catalog # | MBS9210033 |
Price | $165, $370 |
Order / More Info | Mouse Rad50 (C-term), 911-938 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |